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    Collection

    Patents [0/42]
    Periodical Articles [141/141]
    Conference Papers/Meeting Abstract [30/48]

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    Showing items 26-50 of 231. (10 Page(s) Totally)
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    DateTitleRelation
    2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Bioorganic Chemistry. 2020 May;98:Article number 103689.
    2020-03-01 A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis Cancer Letters. 2020 Mar 1;472:97-107.
    2020-01 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Biochimie. 2020 Jan;168:220-230.
    2019-12 Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517.
    2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
    2019-10-08 Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity Advanced Therapeutics. 2019 Oct 8;2(12):Article number 1900105.
    2019-10 Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer Annals of Oncology. 2019 Oct;30(Suppl. 5):789.
    2019-10 The molecular mechanisms of EpCAM in regulating tumor progression and development of anti-EpCAM antibodies for colon cancer diagnosis and therapy Annals of Oncology. 2019 Oct;30(Suppl. 5):786.
    2019-07-03 Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study Journal of Biomolecular Structure and Dynamics. 2019 Jul 3;37(10):2581-2592.
    2019-07 Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation Scientific Reports. 2019 Jul;9:Article number 9943.
    2019-05-29 Insights for the design of protein lysine methyltransferase G9a inhibitors Future Medicinal Chemistry. 2019 May 29;11(9):993-1014.
    2018-11 Biomimetic Syntheses of (±)‐Isopalhinine A, (±)‐Palhinine A, and (±)‐Palhinine D Angewandte Chemie. 2018 Nov;57(47):15572-15576.
    2018-07 Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789.
    2018-07 Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 3944.
    2018-05-10 Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition European Journal of Medicinal Chemistry. 2018 May 10;151:533-545.
    2018-04-25 Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors European Journal of Medicinal Chemistry. 2018 Apr 25;150:491-505.
    2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer Cancer Science. 2018 Jan;109(Suppl. 1):739.
    2017-08-11 Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer Scientific Reports. 2017 Aug 11;7:Article number 7972.
    2017-07 Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors Journal of Biomolecular Structure and Dynamics. 2017 Jun;35(8):1833-1848.
    2017-04 Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
    2017-04 Toward the total syntheses of natural products containing trans-decalin skeleton from masked o-benzoquinone Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 516.
    2017-04 One-pot tandem oxidative dearomatization/ 4+3 cycloaddition: Masked o-benzoquinone with diaza-oxyallyl cation Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 185.
    2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Oncotarget. 2016 Dec;7(52):86239-86256.
    2016-11-29 Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
    2016-07 Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792 Expert Opinion on Therapeutic Patents. 2016 Jul;26(7):751-755.

    Showing items 26-50 of 231. (10 Page(s) Totally)
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