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    最後更新時間: 2025-04-19 12:41

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    Showing items 26-50 of 261. (11 Page(s) Totally)
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    DateTitleRelation
    2022-03-11 以雜環化合物作為激酶抑制劑的治療用途 TWI757722/2022-03-11
    2022-01-21 Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma Journal of Biomedical Science. 2022 Jan 21;29:Article number 5.
    2021-11-15 Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
    2021-10-14 Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
    2021-07-16 Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
    2021-04-16 Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors Organic Process Research and Development. 2021 Apr 16;25(4):817-830.
    2021-04-13 Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kükenthal, 1908) Tetrahedron Letters. 2021 Apr 13;69:Article number 152976.
    2021-02-22 Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design ACS Omega. 2021 Feb 22;6(9):6100-6111.
    2021-01-31 Briarenols W-Z: Chlorine-containing polyoxygenated briaranes from octocoral briareum stechei (Kükenthal, 1908) Marine Drugs. 2021 Jan 31;19(2):Article number 77.
    2021-01-15 One-pot synthesis of dibenzo[b,f]oxepines and total synthesis of bauhinoxepin C Journal of Organic Chemistry. 2021 Jan 15;86(2):1955-1963.
    2021-01 Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.
    2020-12-10 Tumor-agnostic inhibitors in oncology: A new phase for precision medicine Journal of the Chinese Chemical Society. 2020 Dec 10;67(12):2216-2224.
    2020-08 Design of a potent anticancer lead inspired by natural products from traditional Indian medicine Journal of Biomolecular Structure and Dynamics. 2020 Aug;38(12):3563-3577.
    2020-07 Design of drug-like hepsin inhibitors against prostate cancer and kidney stones Acta Pharmaceutica Sinica B. 2020 Jul;10(7):1309-1320.
    2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Bioorganic Chemistry. 2020 May;98:Article number 103689.
    2020-03-01 A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis Cancer Letters. 2020 Mar 1;472:97-107.
    2020-01 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Biochimie. 2020 Jan;168:220-230.
    2019-12 Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517.
    2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
    2019-10-08 Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity Advanced Therapeutics. 2019 Oct 8;2(12):Article number 1900105.
    2019-10 Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer Annals of Oncology. 2019 Oct;30(Suppl. 5):789.
    2019-10 The molecular mechanisms of EpCAM in regulating tumor progression and development of anti-EpCAM antibodies for colon cancer diagnosis and therapy Annals of Oncology. 2019 Oct;30(Suppl. 5):786.
    2019-07-03 Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study Journal of Biomolecular Structure and Dynamics. 2019 Jul 3;37(10):2581-2592.
    2019-07 Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation Scientific Reports. 2019 Jul;9:Article number 9943.
    2019-05-29 Insights for the design of protein lysine methyltransferase G9a inhibitors Future Medicinal Chemistry. 2019 May 29;11(9):993-1014.

    Showing items 26-50 of 261. (11 Page(s) Totally)
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