Collection 專利 [0/42] 期刊論文 [141/141] 會議論文/會議摘要 [30/48] Siblings 伍素瑩 [52/65] 其他 [58/60] 夏克山 [76/98] 岳嶽 [29/32] 張仲明 [7/9] 張俊彥 [18/18] 張竣評 [21/26] 徐祖安 [170/215] 李秀珠 [75/105] 李靜琪 [23/24] 林書玉 [19/20] 洪明秀 [31/40] 潘秀玲(2009-2013) [16/17] 王文傑 [13/15] 王鴻俊 [7/7] 石全(2014-2017) [35/39] 童俊維 [23/23] 紀雅惠 [21/25] 翁紹華 [22/24] 莊宏 [1/1] 葉修華 [24/25] 葉燈光 [133/152] 蔣維棠 [41/66] 趙宇生(2002-2013) [120/212] 郭靜娟 [49/55] 鄒倫 [28/29] 陳志豪 [31/52] 陳新(2002-2015) [53/67] 陳炯東 [180/212] 顏婉菁 [6/7] 許明珠(1997-2001) [3/10] 陳淑貞(1998-2001) [3/11] 陳華鍵(1997-2001) [9/9] Community Statistics 近3年內發表的文件:13(5.63%) 含全文筆數:171(74.03%) 文件下載次數統計 下載大於0次:171(100.00%) 下載大於100次:168(98.25%) 檔案下載總次數:101886(1.90%) 最後更新時間: 2024-12-01 03:15 Top Upload Loading... Top Download Loading... Recent Submissions DBPR116, a prodrug of BPRMU191, in ... Discovery of dual MER/AXL kinase in... Macrophage-mediated controlled rele... Targeting cathepsin S promotes acti... Discovery of novel AXL and MER inhi... Influence of ring strain on the for... A dual nociceptin and mu opioid rec... Development of furanopyrimidine-bas... A critical overview of current prog... Recent advances in total synthesis ...

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Showing items 26-50 of 231. (10 Page(s) Totally) << < 1 2 3 4 5 6 7 8 9 10 > >> View [10|25|50] records per page

Date	Title	Relation
2020-05	Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors	Bioorganic Chemistry. 2020 May;98:Article number 103689.
2020-03-01	A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis	Cancer Letters. 2020 Mar 1;472:97-107.
2020-01	Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening	Biochimie. 2020 Jan;168:220-230.
2019-12	Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry	Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517.
2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
2019-10-08	Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity	Advanced Therapeutics. 2019 Oct 8;2(12):Article number 1900105.
2019-10	Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer	Annals of Oncology. 2019 Oct;30(Suppl. 5):789.
2019-10	The molecular mechanisms of EpCAM in regulating tumor progression and development of anti-EpCAM antibodies for colon cancer diagnosis and therapy	Annals of Oncology. 2019 Oct;30(Suppl. 5):786.
2019-07-03	Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study	Journal of Biomolecular Structure and Dynamics. 2019 Jul 3;37(10):2581-2592.
2019-07	Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation	Scientific Reports. 2019 Jul;9:Article number 9943.
2019-05-29	Insights for the design of protein lysine methyltransferase G9a inhibitors	Future Medicinal Chemistry. 2019 May 29;11(9):993-1014.
2018-11	Biomimetic Syntheses of (±)‐Isopalhinine A, (±)‐Palhinine A, and (±)‐Palhinine D	Angewandte Chemie. 2018 Nov;57(47):15572-15576.
2018-07	Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer	Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789.
2018-07	Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer	Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 3944.
2018-05-10	Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition	European Journal of Medicinal Chemistry. 2018 May 10;151:533-545.
2018-04-25	Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors	European Journal of Medicinal Chemistry. 2018 Apr 25;150:491-505.
2018-01	Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer	Cancer Science. 2018 Jan;109(Suppl. 1):739.
2017-08-11	Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer	Scientific Reports. 2017 Aug 11;7:Article number 7972.
2017-07	Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors	Journal of Biomolecular Structure and Dynamics. 2017 Jun;35(8):1833-1848.
2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
2017-04	Toward the total syntheses of natural products containing trans-decalin skeleton from masked o-benzoquinone	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 516.
2017-04	One-pot tandem oxidative dearomatization/ 4+3 cycloaddition: Masked o-benzoquinone with diaza-oxyallyl cation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 185.
2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Oncotarget. 2016 Dec;7(52):86239-86256.
2016-11-29	Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design	European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
2016-07	Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792	Expert Opinion on Therapeutic Patents. 2016 Jul;26(7):751-755.

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