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日期	题名	關聯
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Jul 17;Article in Press.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-05-19	Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins	Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-01	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	Translational Oncology. 2021 Jan;14(1):Article number 100897.
2020-10-08	Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery	Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-08	BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification	Cancer Research. 2020 Aug;80(16):1937.

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