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    Items for Author "Yeh, T. K." 

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    Showing 152 items.

    Collection Date Title Relation Bitstream
    [伍素瑩] 期刊論文 2020-02-10 Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors -
    [伍素瑩] 期刊論文 2019-04-10 Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants -
    [伍素瑩] 期刊論文 2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening -
    [其他] 期刊論文 2022-07-24 Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice -
    [劉滄梧] 期刊論文 2020-02-18 Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system -
    [夏克山] 專利 2014-11-19 咪唑-4-酮及咪唑-4-硫酮化合物 -
    [夏克山] 專利 2014-04-21 咪唑-4-酮及咪唑-4-硫酮化合物 -
    [夏克山] 專利 2013-01-15 Imidazol-4-one and imidazole-4-thione compounds -
    [夏克山] 期刊論文 2022-10-03 Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention -
    [夏克山] 期刊論文 2021-03-30 A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment -
    [夏克山] 期刊論文 2018-02-08 Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond -
    [夏克山] 期刊論文 2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice -
    [夏克山] 期刊論文 2010-09 Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist -
    [夏克山] 期刊論文 2009-07-23 Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice -
    [岳嶽] 期刊論文 2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems -
    [岳嶽] 期刊論文 2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor -
    [廖玉潔] 期刊論文 2024-08-19 Tracing the footprints of MPXV in Asia: Phylogenetic insights and lineage dynamics -
    [張俊彥] 期刊論文 2022-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy -
    [張俊彥] 期刊論文 2018-06-15 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] -
    [張俊彥] 期刊論文 2016-01 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition -
    [張俊彥] 期刊論文 2014-05 Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells -
    [張俊彥] 期刊論文 2014-04 Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones -
    [張俊彥] 期刊論文 2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells -
    [張俊彥] 期刊論文 2009-04-17 Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents -
    [徐祖安] 會議論文/會議摘要 2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study -
    [徐祖安] 會議論文/會議摘要 2011-03 Potent EGFR tyrosine kinase inhibitors as anticancer agents -
    [徐祖安] 期刊論文 2014-01-08 Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer -
    [徐祖安] 期刊論文 2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML -
    [李秀珠] 會議論文/會議摘要 2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents -
    [李秀珠] 期刊論文 2020-08 Repurposing old drugs as antiviral agents for coronaviruses -
    [李秀珠] 期刊論文 2017-07 Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors -
    [李靜琪] 期刊論文 2023-10-05 Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease -
    [李靜琪] 期刊論文 2019-03 Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors -
    [李靜琪] 期刊論文 2018-01-01 Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 -
    [李靜琪] 期刊論文 2016-05 N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors -
    [李靜琪] 期刊論文 2012-09 Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors -
    [林嬪嬪] 會議論文/會議摘要 2007-10 Differential effects of arsenic on cyp1 enzymes in vitro and in vivo -
    [林嬪嬪] 期刊論文 2009-02 Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: An in vitro and in vivo study -
    [林嬪嬪] 期刊論文 2007-09 Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment -
    [楊重熙] 期刊論文 2011-03 Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications -
    [洪明秀] 會議論文/會議摘要 2016-12 Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy -
    [洪明秀] 期刊論文 2010-10 Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities -
    [石全(2014-2017)] 會議論文/會議摘要 2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification -
    [紀雅惠] 會議論文/會議摘要 2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer -
    [紀雅惠] 期刊論文 2024-06-01 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus -
    [紀雅惠] 期刊論文 2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins -
    [翁紹華] 會議論文/會議摘要 2018-07 4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo -
    [翁紹華] 期刊論文 2022-12-05 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation -
    [翁紹華] 期刊論文 2022-02-05 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design -
    [翁紹華] 期刊論文 2018-04 4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy -
    [翁紹華] 期刊論文 2017-05 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine -
    [翁紹華] 期刊論文 2017-01 Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists -
    [翁紹華] 期刊論文 2016-01 Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy -
    [葉修華] 期刊論文 2024-10-29 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration -
    [葉修華] 期刊論文 2024-07-17 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia -
    [葉修華] 期刊論文 2023-10-05 A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects -
    [葉修華] 期刊論文 2020-04 BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine -
    [葉燈光] 專利 2014-08-15 Anticancer oral formulation -
    [葉燈光] 專利 2014-06-04 抗癌口服制剂 -
    [葉燈光] 專利 2013-06-05 Anticancer oral formulation -
    [葉燈光] 專利 2013-02-11 抗癌口服藥學組成物 -
    [葉燈光] 專利 2011-09-27 Formulations of indol-3-yl-2-oxoacetamide compounds -
    [葉燈光] 會議論文/會議摘要 2019-10 Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer -
    [葉燈光] 會議論文/會議摘要 2017-04 Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation -
    [葉燈光] 會議論文/會議摘要 2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 -
    [葉燈光] 期刊論文 2022-12-05 2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors -
    [葉燈光] 期刊論文 2020-02-01 Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment -
    [葉燈光] 期刊論文 2019-06-05 Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice -
    [葉燈光] 期刊論文 2019-05 Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents -
    [葉燈光] 期刊論文 2018-08-23 5-aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating alzheimer's disease phenotypes -
    [葉燈光] 期刊論文 2016-09 Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice -
    [葉燈光] 期刊論文 2016-07 In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71 -
    [葉燈光] 期刊論文 2015-01 1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells -
    [葉燈光] 期刊論文 2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent -
    [葉燈光] 期刊論文 2013-07-08 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors -
    [葉燈光] 期刊論文 2013-07-08 Inside Cover: 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors(ChemBioChem 10/2013) -
    [葉燈光] 期刊論文 2012-12-13 Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity -
    [葉燈光] 期刊論文 2012-06 Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats -
    [葉燈光] 期刊論文 2012-04 Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo -
    [葉燈光] 期刊論文 2012-02-01 Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature -
    [葉燈光] 期刊論文 2011-03 Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet -
    [葉燈光] 期刊論文 2009-07 Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes -
    [葉燈光] 期刊論文 2008-07 Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice -
    [葉燈光] 期刊論文 2008-05 High-performance liquid chromatography-electrospray mass spectrometry for the simultaneous determination of multiple active components in Sheng-Mai San, a prescription of traditional Chinese medicine -
    [葉燈光] 期刊論文 2008-02-28 Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet -
    [葉燈光] 期刊論文 2008-02 The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes -
    [葉燈光] 期刊論文 2007-10-01 Rapid and sensitive determination of fentanyl in dog plasma by on-line solid-phase extraction integrated with a hydrophilic column coupled to tandem mass spectrometry -
    [葉燈光] 期刊論文 2007-09-15 Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry -
    [葉燈光] 期刊論文 2007-07 Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes -
    [葉燈光] 期刊論文 2006-11-25 The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes -
    [蔣維棠] 期刊論文 2021-01 Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease -
    [蔣維棠] 期刊論文 2019-12 Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia -
    [蔣維棠] 期刊論文 2015-07 Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations -
    [蔣維棠] 期刊論文 2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2009-04-01 Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors -
    [蔣維棠] 期刊論文 2009-03-15 Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors -
    [謝興邦] 會議論文/會議摘要 2023-10 Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs -
    [謝興邦] 會議論文/會議摘要 2014-11 Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent -
    [謝興邦] 會議論文/會議摘要 2014-10 Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma -
    [謝興邦] 會議論文/會議摘要 2013-04-07 BPR000K, a novel Aurora kinase inhibitor -
    [謝興邦] 會議論文/會議摘要 2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor -
    [謝興邦] 會議論文/會議摘要 2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 -
    [謝興邦] 會議論文/會議摘要 2011-03-27 Design and synthesis of potent Aurora kinase inhibitors -
    [謝興邦] 期刊論文 2024-06-24 Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment -
    [謝興邦] 期刊論文 2023-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2021-11-15 Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization -
    [謝興邦] 期刊論文 2021-10-14 Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model -
    [謝興邦] 期刊論文 2021-01 Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors -
    [謝興邦] 期刊論文 2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors -
    [謝興邦] 期刊論文 2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2017-08-11 Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer -
    [謝興邦] 期刊論文 2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation -
    [謝興邦] 期刊論文 2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor -
    [謝興邦] 期刊論文 2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization -
    [謝興邦] 期刊論文 2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents -
    [謝興邦] 期刊論文 2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach -
    [謝興邦] 期刊論文 2007-02-01 Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study -
    [謝興邦] 期刊論文 2006-10 Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents -
    [趙宇生(2002-2013)] 會議論文/會議摘要 2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia -
    [趙宇生(2002-2013)] 期刊論文 2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes -
    [趙宇生(2002-2013)] 期刊論文 2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus -
    [趙宇生(2002-2013)] 期刊論文 2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency -
    [趙宇生(2002-2013)] 期刊論文 2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors -
    [趙宇生(2002-2013)] 期刊論文 2010-08 Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein -
    [趙宇生(2002-2013)] 期刊論文 2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 -
    [郭靜娟] 期刊論文 2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway -
    [鄒倫] 期刊論文 2022-07 Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate -
    [鄒倫] 期刊論文 2022-06-21 Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids -
    [鄒倫] 期刊論文 2022-02-15 Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates -
    [鄒倫] 期刊論文 2021-01 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy -
    [鄒倫] 期刊論文 2019-07-11 Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates -
    [鄒倫] 期刊論文 2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates -
    [鄒小蕙] 期刊論文 2013-07 CYP1A2 genetic polymorphisms are associated with early antidepressant escitalopram metabolism and adverse reactions -
    [陳志豪] 期刊論文 2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus -
    [陳志豪] 期刊論文 2017-01 A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide -
    [陳新(2002-2015)] 期刊論文 2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV -
    [陳新(2002-2015)] 期刊論文 2009-07-15 Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor -
    [陳炯東] 會議論文/會議摘要 2019-07 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy -
    [陳炯東] 會議論文/會議摘要 2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer -
    [陳炯東] 會議論文/會議摘要 2016-12 Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST -
    [陳炯東] 會議論文/會議摘要 2015-08 Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform -
    [陳炯東] 會議論文/會議摘要 2015-08 Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia -
    [陳炯東] 期刊論文 2022-10-13 Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate -
    [陳炯東] 期刊論文 2021-08-01 DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity -
    [陳炯東] 期刊論文 2020-08 Artificial intelligence approach fighting COVID-19 with repurposing drugs -
    [陳炯東] 期刊論文 2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities -
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