國家衛生研究院 NHRI:
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    顯示項目101-125 / 215. (共9頁)
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    日期題名關聯
    2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
    2012-06 EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells Molecular Oncology. 2012 Jun;6(3):299-310.
    2012-05-11 作為極光激酶抑制劑之稠合雙環嘧啶化合物 I363627/2012-05-11
    2012-04-11 咪唑啉酮及咪唑啉硫酮衍生物 I361808/2012-04-11
    2012-03-25 Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
    2012-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors US8138194B2/2012-03-20
    2012-03-01 C型肝炎病毒抑制劑 I359137/2012-03-01
    2012-02 Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents Investigational New Drugs. 2012 Feb;30(1):164-175.
    2012-02 Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus Antimicrobial Agents and Chemotherapy. 2012 Feb;56(2):647-657.
    2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
    2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML British Journal of Cancer. 2012 Jan;106(3):475-481.
    2012-01 A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors Anticancer Research. 2012 Jan;32(1):147-151.
    2011-12 Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism Biotechnology and Bioengineering. 2011 Dec;108(12):2932-2940.
    2011-09-23 BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo European Journal of Cancer. 2011 Sep 23;47:S127.
    2011-09 Overcoming the acquired resistance to Afatinib (BIBW2992) in HCC827, a non-small cell lung cancer cell line European Journal of Cancer. 2011 Sep;47:S129.
    2011-09 Suppression of stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells European Journal of Cancer. 2011 Sep;47(Suppl. 1):S104.
    2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells PLoS ONE. 2011 Aug;6(8):Article number e23485.
    2011-07-26 Hepatitis C virus inhibitors US7985763B2/2011-07-26
    2011-07-11 抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物 I344959/2011-07-11
    2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
    2011-06-21 抑制冠狀病毒之醫藥組合物 I343809/2011-06-21
    2011-06-21 抑制冠狀病毒之醫藥組合物 I343808/2011-06-21
    2011-06-21 抑制冠狀病毒之醫藥組合物 I343810/2011-06-21
    2011-06-01 Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells Biochemical Pharmacology. 2011 Jun 01;81(11):1263-1270.
    2011-06 Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir Journal of Infectious Diseases. 2011 Jun;203(12):1784-1790.

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