| 2012-06 |
Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats |
Journal of Ethnopharmacology. 2012 Jun;142(1):121-128. |
 |
| 2012-06 |
Involvement of transcriptional regulator Ndt80 in stress responses of Candida albicans |
Mycoses. 2012 Jun;55(Suppl. S4):131-132. |
|
| 2012-05-11 |
作為極光激酶抑制劑之稠合雙環嘧啶化合物 |
I363627/2012-05-11 |
|
| 2012-05 |
Palladium(II) acetate mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones for facile construction of methylenecyclohexane ring system |
Organic & Biomolecular Chemistry. 2012 May;10(23):4609-4617. |
|
| 2012-04-21 |
吡咯啉啶化合物 |
I362388/2012-04-21 |
|
| 2012-04-11 |
咪唑啉酮及咪唑啉硫酮衍生物 |
I361808/2012-04-11 |
|
| 2012-04 |
Securin enhances the anti-cancer effects of 6-Methoxy-3-(3′,4′,5′-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in human colorectal cancer cells |
PLoS ONE. 2012 Apr;7(4):Article number e36006. |
|
| 2012-04 |
Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo |
Journal of Medicinal Chemistry. 2012 Apr;55(8):3777-3791. |
|
| 2012-03-25 |
Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI. |
|
| 2012-03-20 |
Fused bicyclic pyrimidine compounds as aurora kinase inhibitors |
US8138194B2/2012-03-20 |
|
| 2012-03-06 |
Indole compounds |
CA2437104/2012-03-06 |
|
| 2012-03-01 |
C型肝炎病毒抑制劑 |
I359137/2012-03-01 |
|
| 2012-03 |
R432 is a key residue for the multiple functions of Ndt80p in Candida albicans |
Cellular and Molecular Life Sciences. 2012 Mar;69(6):1011-1023. |
|
| 2012-02-01 |
Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines |
Cancer Letters. 2012 Feb 1;315(1):1-11. |
|
| 2012-02-01 |
Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature |
Nanotechnology. 2012 Feb 1;23(8):Article number 085102. |
|
| 2012-02 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents |
Investigational New Drugs. 2012 Feb;30(1):164-175. |
|
| 2012-02 |
Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus |
Antimicrobial Agents and Chemotherapy. 2012 Feb;56(2):647-657. |
|
| 2012-02 |
Discovery of novel stem cell mobilizers that target the CXCR4 receptor |
ChemMedChem. 2012 Feb;7(2):209-212. |
|
| 2012-02 |
Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of Akt/GSK-3beta and mTOR signaling pathways |
PLoS ONE. 2012 Feb;7(2):Article number e31195. |
|
| 2012-01-17 |
Pyrrolidine compounds |
CA2559611/2012-01-17 |
|
| 2012-01 |
QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells |
Cancer Science. 2012 Jan;103(1):80-87. |
|
| 2012-01 |
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor |
Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53. |
|
| 2012-01 |
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML |
British Journal of Cancer. 2012 Jan;106(3):475-481. |
|
| 2012-01 |
A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors |
Anticancer Research. 2012 Jan;32(1):147-151. |
|
| 2011-12-06 |
Pyrrolidine compounds |
US8071787B2/2011-12-06 |
|
| 2011-12 |
Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism |
Biotechnology and Bioengineering. 2011 Dec;108(12):2932-2940. |
|
| 2011-12 |
Antitumor activity of a novel histone deacetylase inhibitor (S)-HDAC42 in oral squamous cell carcinoma |
Oral Oncology. 2011 Dec;47(12):1127-1133. |
|
| 2011-11-15 |
Coumarin compounds and their use for treating cancer |
US8058427B2/2011-11-15 |
|
| 2011-11-04 |
Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9 |
FEBS Letters. 2011 Nov 4;585(21):3409-3414. |
|
| 2011-11 |
A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells |
Cell Death and Differentiation. 2011 Nov;18(11):1791-1804. |
|
| 2011-11 |
Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the formosan tylophora ovata |
Planta Medica. 2011 Nov;77(17):1932-1938. |
|
| 2011-11 |
Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins |
Biomaterials. 2011 Nov;32(33):8712-8721. |
|
| 2011-10-01 |
硒吩化合物及其醫藥組成物 |
I349668/2011-10-01 |
|
| 2011-10 |
Antiproliferative effects of N-heterocyclic indolyl glyoxylamide derivatives on human lung cancer cells |
Anticancer Research. 2011 Oct;31(10):3407-3415. |
|
| 2011-09-27 |
Formulations of indol-3-yl-2-oxoacetamide compounds |
US8026271B2/2011-09-27 |
|
| 2011-09-23 |
BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo |
European Journal of Cancer. 2011 Sep 23;47:S127. |
|
| 2011-09-20 |
Pyrrolidine derivatives |
US8022096B2/2011-09-20. |
|
| 2011-09 |
Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents |
European Journal of Medicinal Chemistry. 2011 Sep;46(9):3623-3629. |
|
| 2011-09 |
Proline in transmembrane domain of type II protein DPP-IV governs Its translocation behavior through endoplasmic reticulum |
Biochemistry. 2011 Sep;50(37):7909-7918. |
|
| 2011-09 |
Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway |
Journal of Virology. 2011 Sep;85(17):9114-9126 |
|
| 2011-09 |
Hypervalent iodine(iii) sulfonate mediated synthesis of 6-arylimidazo[2,1-b]thiazoles in liquid PEG-400 |
Journal of the Chinese Chemical Society. 2011 Sep;58(5):663-666. |
|
| 2011-09 |
Overcoming the acquired resistance to Afatinib (BIBW2992) in HCC827, a non-small cell lung cancer cell line |
European Journal of Cancer. 2011 Sep;47:S129. |
|
| 2011-09 |
Suppression of stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells |
European Journal of Cancer. 2011 Sep;47(Suppl. 1):S104. |
|
| 2011-09 |
Effects of dipeptidyl peptidase 4 inhibition with MK-0431 on syngeneic mouse islet transplantation |
Diabetologia. 2011 Sep;54(Suppl. 1):S181. |
|
| 2011-08-11 |
噁二唑化合物 |
I346662/2011-08-11 |
|
| 2011-08 |
Colloid-based multiplexed screening for plant biomass-degrading glycoside hydrolase activities in microbial communities |
Energy and Environmental Science. 2011 Aug;4(8):2884-2893. |
|
| 2011-08 |
Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): Is DPP8-selectivity an attainable goal? |
Journal of Medicinal Chemistry. 2011 Aug;54(16):5737-5746. |
|
| 2011-08 |
BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells |
PLoS ONE. 2011 Aug;6(8):Article number e23485. |
|
| 2011-07-26 |
Hepatitis C virus inhibitors |
US7985763B2/2011-07-26 |
|
| 2011-07-25 |
The first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside |
Chemistry-A European Journal. 2011 Jul 25;17(31):8696-8703. |
|
