| 2011-07-11 |
抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物 |
I344959/2011-07-11 |
|
| 2011-07 |
Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model |
Laboratory Investigation. 2011 Jul;91(7):1029-1039. |
 |
| 2011-07 |
Conia-ene annulation of the alpha-cyano Beta-TMS-capped alkynyl cycloalkanone system and its synthetic application |
Organic and Biomolecular Chemistry. 2011 Jul;9(13):4778-4781. |
|
| 2011-07 |
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 . |
|
| 2011-06-21 |
抑制冠狀病毒之醫藥組合物 |
I343809/2011-06-21 |
|
| 2011-06-21 |
抑制冠狀病毒之醫藥組合物 |
I343808/2011-06-21 |
|
| 2011-06-21 |
抑制冠狀病毒之醫藥組合物 |
I343810/2011-06-21 |
|
| 2011-06-01 |
Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells |
Biochemical Pharmacology. 2011 Jun 01;81(11):1263-1270. |
|
| 2011-06 |
Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate |
Journal of Biochemistry. 2011 Jun;149(6):685-692. |
|
| 2011-06 |
Development of sodium-dependent glucose co-transporter 2 inhibitors as potential anti-diabetic therapeutics |
Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1476-1512. |
|
| 2011-06 |
Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein |
Current Topics In Medicinal Chemistry. 2011 Jun;(11):1447-1463. |
|
| 2011-06 |
Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir |
Journal of Infectious Diseases. 2011 Jun;203(12):1784-1790. |
|
| 2011-06 |
Drug discovery in enteroviral infections |
Infectious Disorders-Drug Targets. 2011 Jun;11(3):337-345. |
|
| 2011-06 |
Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10) |
Expert Opinion on Therapeutic Patents. 2011 Jun;21(6):857-884. |
|
| 2011-06 |
A new perspective of cannabinoid 1 receptor antagonists: Approaches toward peripheral CB1R blockers without crossing the blood-brain barrier |
Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1421-1429. |
|
| 2011-06 |
Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome |
Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1420. |
|
| 2011-05-25 |
Pyrrolidine derivatives |
ZA201006329B/2011-05-25 |
|
| 2011-05-10 |
Imidazolidinone and imidazolidinethione derivatives |
US7939523B2/2011-05-10 |
|
| 2011-05 |
Selective inhibition of early-but not late-expressed HIF-1alpha is neuroprotective in rats after focal ischemic brain damage |
Brain Pathology. 2011 May;21(3):249-262. |
|
| 2011-05 |
Costunolide induces apoptosis through nuclear calcium2+ overload and DNA damage response in human prostate cancer |
Journal of Urology. 2011 May;185(5):1967-1974. |
|
| 2011-05 |
Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4 |
Journal of Agricultural and Food Chemistry. 2011 May;59(9):4644-4648. |
|
| 2011-05 |
Study of glioblastoma multiforme metastatic and invasive mechanism by polycistronic imaging probe in tumor implanted animal model |
Journal of Nuclear Medicine. 2011 May;52(Suppl. 1):Meeting Abstract 1709. |
|
| 2011-04-28 |
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents |
Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080. |
|
| 2011-04-25 |
Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus |
Journal of Natural Products. 2011 Apr 25;74(4):580-584. |
|
| 2011-04-06 |
Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders |
EP1506960/2011-04-06 |
|
| 2011-04 |
Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer |
Investigational New Drugs. 2011 Apr;29(2):195-206. |
|
| 2011-04 |
Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2011 Apr;21(7):1948-1952. |
|
| 2011-04 |
Antivascular activities of novel tubulin binding agent BPR0L075 |
Cancer Research. 2011 Apr;71:Abstract number 5309. |
|
| 2011-03-27 |
Design and synthesis of potent Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI. |
|
| 2011-03-21 |
吡唑化合物及其醫藥組成物 |
I339205/2011-03-21 |
|
| 2011-03-07 |
2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors |
ChemMedChem. 2011 Mar 7;6(3):450-456. |
|
| 2011-03-04 |
Autoxidative annulation cascade of the alpha-cyano beta-TMS-capped alkynyl cycloalkanone system |
Organic Letters. 2011 Mar 4;13(5):896-899. |
|
| 2011-03-01 |
Thiourea derivatives |
US7897764B2/2011-03-01 |
|
| 2011-03 |
Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications |
Nanotoxicology. 2011 Mar;5(1):91-97. |
|
| 2011-03 |
Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes |
Journal of Virology. 2011 Mar;85(6):2927-2941. |
|
| 2011-03 |
Processing and turnover of the Hedgehog protein in the endoplasmic reticulum |
Journal of Cell Biology. 2011 Mar;192(5):825-838. |
|
| 2011-03 |
Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet |
Journal of Food and Drug Analysis. 2011 Mar;19(1):40-48. |
|
| 2011-03 |
Potent EGFR tyrosine kinase inhibitors as anticancer agents |
Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI. |
|
| 2011-03 |
SAR studies of quinoline derivatives as novel anti-influenza agents |
Abstracts of Papers - American Chemical Society. 2011 Mar;241:81-MEDI. |
|
| 2011-02 |
Dowex-50w promoted friedlander synthesis of substituted quinolines under solvent-free conditions |
Heterocycles. 2011 Feb;83(2):331-338. |
|
| 2011-02 |
Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability |
Journal of the Chinese Chemical Society. 2011 Feb;58(1):108-117. |
|
| 2011-01-13 |
Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes |
Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178. |
|
| 2011-01 |
Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay |
Antimicrobial Agents and Chemotherapy. 2011 Jan;55(1):229-238. |
|
| 2011-01 |
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities |
Cancer Science. 2011 Jan;102(1):182-191. |
|
| 2011-01 |
Antitubercular resorcinol analogs and benzenoid C-glucoside from the roots of ardisia cornudentata |
Planta Medica. 2011 Jan;77(1):60-65. |
|
| 2010-12-01 |
吲哚化合物 |
ZL200480034988.8/2010-12-01 |
|
| 2010-12-01 |
抗肿瘤化合物 |
ZL200580045509.7/2010-12-01 |
|
| 2010-12 |
Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening |
Journal of Medicinal Chemistry. 2010 Dec;53(24):8770-8774. |
|
| 2010-12 |
Downregulation of signaling-active IGF-1 by dipeptidyl peptidase IV (DPP-IV) |
International Journal of Biomedical Science. 2010 Dec;6(4):301-309. |
|
| 2010-11-16 |
Thiophene compounds |
US7834046B2/2010-11-16 |
|
