| 2010-01 |
BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses |
Journal of Antimicrobial Chemotherapy. 2010 Jan;65(1):63-71. |
 |
| 2009-12-15 |
Indole compounds |
US7632955B2/2009-12-15 |
|
| 2009-12-01 |
芳香羰吲哚化合物 |
I317634/2009-12-01 |
|
| 2009-12 |
Cytotoxic alkyl benzoquinones and alkyl phenols from Ardisia virens |
Phytochemistry. 2009 Dec;70(17-18):2064-2071. |
|
| 2009-12 |
Antitubercular resorcinols and cytotoxic alkyl benzoquinones from Ardisia kusukuensis |
Taiwan Pharmaceutical Journal. 2009 Dec;61(4):89-105. |
|
| 2009-11-01 |
Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Nov 1;19(21):6063-6068. |
|
| 2009-11 |
Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection |
Antimicrobial Agents and Chemotherapy. 2009 Nov;53(11):4825-4834. |
|
| 2009-11 |
Viral and host proteins involved in picornavirus life cycle |
Journal of Biomedical Science. 2009 Nov;16(1):Article number 103 |
|
| 2009-10-07 |
Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection |
EP1627635/2009-10-07 |
|
| 2009-10 |
Gd(OTf)(3)- Bmim PF6: A novel and recyclable catalytic system for the synthesis of quinolines |
Journal of the Chinese Chemical Society. 2009 Oct;56(5):867-872. |
|
| 2009-10 |
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases |
Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055. |
|
| 2009-09-03 |
Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis |
FEBS Letters. 2009 Sep 3;583(17):2765-2771. |
|
| 2009-09 |
Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development |
EJC Supplements. 2009 Sep;7(2):96. |
|
| 2009-08-14 |
Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression |
Biochemical and Biophysical Research Communications. 2009 Aug 14;386(1):140-145. |
|
| 2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945. |
|
| 2009-08-04 |
Imidazolamino compounds |
US7569596B2/2009-08-04 |
|
| 2009-08-01 |
Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Aug 1;19(15):4134-4138. |
|
| 2009-08 |
An efficient protocol for the synthesis of N-Alkyl- and N-Arylimides using the lewis acidic ionic liquid choline chloride center dot 2ZnCl(2) |
Journal of the Chinese Chemical Society. 2009 Aug;56(4):839-842. |
|
| 2009-08 |
Hypervalent Iodine(III) Sulfonate Mediated Synthesis of Quinoxalines in Liquid PEG-400 |
Journal of the Chinese Chemical Society. 2009 Aug;56(4):683-687. |
|
| 2009-07-23 |
Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4496-4510. |
|
| 2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233. |
|
| 2009-07-15 |
Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor |
Biochemical Pharmacology. 2009 Jul 15;78(2):203-210. |
|
| 2009-07-03 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers |
Molecular Cancer. 2009 Jul 3;8:Article number 43. |
|
| 2009-07 |
Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71 |
Antimicrobial Agents and Chemotherapy. 2009 Jul;53(7):2740-2747. |
|
| 2009-07 |
Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes |
Food and Chemical Toxicology. 2009 Jul;47(7):1703-1709. |
|
| 2009-07 |
Additional new 5,6-dihydroflavanones and cytotoxic constituents from the leaves of Cryptocarya chinensis |
Planta Medica. 2009 Jul;75(9):987-988. |
|
| 2009-06-09 |
Treatment of coronavirus infection |
US7544712B1/2009-06-09 |
|
| 2009-06 |
Enzyme Activity and Immunohistochemical Localization of Dipeptidyl Peptidase 8 and 9 in Male Reproductive Tissues |
Journal of Histochemistry and Cytochemistry. 2009 Jun;57(6):531-541. |
|
| 2009-06 |
Secondary metabolites and cytotoxic activities from the stem bark of Zanthoxylum nitidum |
Chemistry and Biodiversity. 2009 Jun;6(6):846-857. |
|
| 2009-06 |
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.] |
European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763. |
|
| 2009-06 |
Hypervalent iodine(III) sulfonate mediated synthesis of 2-arylimidazo[1,2-a]pyrimidines in liquid PEG-400 |
Journal of the Chinese Chemical Society. 2009 Jun;56(3):632-635. |
|
| 2009-06 |
Efficient synthesis of 2-aminothiazoles and fanetizole in liquid PEG-400 at ambient conditions |
Journal of the Chinese Chemical Society. 2009 Jun;56(3):455-458. |
|
| 2009-05-15 |
Biochemical properties and expression profile of human prolyl dipeptidase DPP9 |
Archives of Biochemistry and Biophysics. 2009 May 15;485(2):120-127. |
|
| 2009-05-05 |
Indole compounds |
US7528165B2/2009-05-05 |
|
| 2009-05 |
Down-regulation of survivin enhances sensitivity to BPROL075 in human cancer cells via caspase-independent mechanisms |
Cancer Research. 2009 May;69:Abstract number 5542. |
|
| 2009-04-24 |
Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway |
Journal of Biological Chemistry. 2009 Apr 24;284(17):11121-11133. |
|
| 2009-04-23 |
Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists |
Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622. |
|
| 2009-04-17 |
Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents |
ChemMedChem. 2009 Apr 17;4(4):588-593. |
|
| 2009-04-16 |
Polyene cyclization promoted by the cross-conjugated alpha-carbalkoxy cyclohexenone system. An unusual 1,2-hydride shift under lewis acid catalysis |
Organic Letters. 2009 Apr 16;11(8):1673-1675. |
|
| 2009-04-01 |
Design, synthesis, and anti-HCV activity of thiourea compounds |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1950-1955. |
|
| 2009-04-01 |
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912. |
|
| 2009-04 |
In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery |
Biomaterials. 2009 Apr;30(12):2329-2339. |
|
| 2009-04 |
Aurora kinase inhibitors in preclinical and clinical testing |
Expert Opinion on Investigational Drugs. 2009 Apr;18(4):379-398. |
|
| 2009-03-15 |
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399. |
|
| 2009-03-10 |
Imidazolidinone compounds |
US7501445B2/2009-03-10 |
|
| 2009-03 |
Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells |
Mycological Research. 2009 Mar;113(3):388-390. |
|
| 2009-03 |
Advances in Aurora kinase inhibitor patents |
Expert Opinion on Therapeutic Patents. 2009 Mar;19(3):321-356. |
|
| 2009-03 |
Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2009 Mar;237:MEDI 221. |
|
| 2009-02-26 |
Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity |
Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062. |
|
| 2009-02-21 |
苯噻唑離子化合物 |
I306401/2009-02-21 |
|
