| 2016-11-18 |
Cobalt(II)-catalyzed aerobic oxidation of terminal-capped alkynyl alpha-cyano alkanone systems. An oxygen-mediated radical chain reaction |
Journal of Organic Chemistry. 2016 Nov 18;81(22):10759-10768. |
 |
| 2016-10 |
Cytotoxic cardenolides and sesquiterpenoids from the fruits of Reevesia formosana |
Phytochemistry. 2016 Oct;130:282-290. |
|
| 2016-10 |
BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia |
Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333. |
|
| 2016-10 |
Multifunctional nanoparticles for oral protein drug delivery |
Diabetes Research and Clinical Practice. 2016 Oct;120(Suppl. 1):S19. |
|
| 2016-09 |
Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy |
Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311. |
|
| 2016-09 |
Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice |
Pharmacological Research. 2016 Sep;111:867-876. |
|
| 2016-08 |
Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
Oncotarget. 2016 Aug;7(31):49310-49321. |
|
| 2016-08 |
Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets |
Diabetologia. 2016 Aug;59(Suppl. 1):S198. |
|
| 2016-07-28 |
Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors |
European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406. |
|
| 2016-07-22 |
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons |
Nature Communications. 2016 Jul 22;7:Article number 12199. |
|
| 2016-07-01 |
MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma |
PLoS ONE. 2016 Jul 1;11(7):Article number e0158440. |
|
| 2016-07 |
In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71 |
Journal of Antimicrobial Chemotherapy. 2016 Jul;71(7):1922-1932. |
|
| 2016-07 |
Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792 |
Expert Opinion on Therapeutic Patents. 2016 Jul;26(7):751-755. |
|
| 2016-07 |
Total synthesis of the naturally occurring glycosylflavone aciculatin |
Journal of Natural Products. 2016 Jul;79(7):1719-1723. |
|
| 2016-06 |
The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury |
Neuropharmacology. 2016 Jun;105:1-9. |
|
| 2016-05-19 |
Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses |
OncoTargets and Therapy. 2016 May 19;9:2961-2973. |
|
| 2016-05 |
N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors |
Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250. |
|
| 2016-05 |
An early granulocyte colony-stimulating factor treatment attenuates neuropathic pain through activation of mu opioid receptors on the injured nerve |
Scientific Reports. 2016 May;6:Article number 25490. |
|
| 2016-04-12 |
Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK) |
Journal of Medicinal Chemistry. 2016 Apr 12;59(8):3906-3919. |
|
| 2016-04 |
Discovery and development of tylophorine derived dibenzoquinolines-33b compounds into therapeutic agents |
The FASEB Journal. 2016 Apr;30(1, Suppl.):Meeting Abstract lb56. |
 |
| 2016-03 |
Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: The impact of P1-variation |
MedChemComm. 2016 Mar;7(3):433-438. |
|
| 2016-03 |
Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin |
RSC Advances. 2016 Mar;6(38):31947-31959. |
|
| 2016-02-26 |
Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development |
Scientific Reports. 2016 Feb 26;6:Article number 21662. |
|
| 2016-02-22 |
Guidelines for the use and interpretation of assays for monitoring autophagy [Erratum to: Autophagy. 2016 Jan 2;12(1):1-222.] |
Autophagy. 2016 Feb 22;12(2):443. |
|
| 2016-02 |
Antibacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates |
Journal of the American Chemical Society. 2016 Feb 24;138(7):2209-2218. |
|
| 2016-02 |
Multifunctional nanoparticles for oral protein drug delivery |
Nanomedicine: Nanotechnology, Biology and Medicine. 2016 Feb;12(2):463. |
|
| 2016-01-02 |
Guidelines for the use and interpretation of assays for monitoring autophagy |
Autophagy. 2016 Jan 2;12(1):1-222. |
|
| 2016-01-01 |
Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors |
Theranostics. 2016 Jan 1;6(1):118-130. |
|
| 2016-01 |
Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions |
Organic and Biomolecular Chemistry. 2016 Jan;14(1):220-228. |
|
| 2016-01 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition |
Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723. |
|
| 2016-01 |
Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1 |
Journal of Medicinal Chemistry. 2016 Jan;59 (1):282-293. |
|
| 2016-01 |
Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy |
Journal of Medicinal Chemistry. 2016 Jan;59(1):419-430. |
|
| 2015-12 |
The dnaJ gene as a molecular discriminator to differentiate among species and strain within the Lactobacillus casei group |
Molecular and Cellular Probes. 2015 Dec;29(6):479-484. |
|
| 2015-12 |
Simultaneous discrimination of species and strains in Lactobacillus rhamnosus using species-specific PCR combined with multiplex mini-sequencing technology |
Molecular and Cellular Probes. 2015 Dec;29(6):531-533. |
|
| 2015-12 |
Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model |
European Journal of Medicinal Chemistry. 2015 Dec;106:60-74. |
|
| 2015-10 |
Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening |
Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819. |
|
| 2015-09 |
O6-Methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma |
International Journal of Cancer. 2015 Sep;137(6):1291-1305. |
|
| 2015-09 |
Self-assembling bubble carriers for oral protein delivery |
Biomaterials. 2015 Sep;64:115-124. |
|
| 2015-08-14 |
Studies on antibiotics active against resistant bacteria. Total synthesis of MRSA-active tetarimycin A and its analogues |
Organic Letters. 2015 Aug 14;17(17):4248-4251. |
|
| 2015-08 |
Sun1 deficiency leads to cerebellar ataxia in mice |
Disease Models and Mechanisms. 2015 Aug;8(8):957-967. |
|
| 2015-08 |
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes |
Bioorganic and Medicinal Chemistry. 2015 Aug;23(15):4230-4236. |
|
| 2015-08 |
Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway |
Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692. |
|
| 2015-08 |
BPR2P001S0, a Coumarin derivative, induced cell cycle arrest in A549 through inhibiting PDPK1 activity |
Cancer Research. 2015 Aug;75:Abstract number 1754. |
|
| 2015-08 |
Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform |
Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413. |
|
| 2015-08 |
Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia |
Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490. |
|
| 2015-08 |
Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma |
Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 180. |
|
| 2015-08 |
Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors |
Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182. |
|
| 2015-07-31 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物 |
HK1151694/2015-07-31 |
|
| 2015-07-29 |
脯氨酸衍生物 |
ZL201080002506.6/2015-07-29 |
|
| 2015-07-22 |
作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 |
ZL200980144458.1/2015-07-22 |
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