國家衛生研究院 NHRI:
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    近3年内发表的文件:90(8.93%)
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    显示项目201-225 / 1008. (共41页)
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    日期题名關聯
    2019-07-03 Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study Journal of Biomolecular Structure and Dynamics. 2019 Jul 3;37(10):2581-2592.
    2019-07 Nucleoside analogs with selective antiviral activity against dengue fever and Japanese encephalitis viruses Antimicrobial Agents and Chemotherapy. 2019 Jul;63(7):e00397-19.
    2019-07 Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation In Vivo. 2019 Jul-Aug;33(4):1193-1201.
    2019-07 Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation Scientific Reports. 2019 Jul;9:Article number 9943.
    2019-07 Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626.
    2019-07 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227.
    2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
    2019-06-15 Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems Advanced Drug Delivery Reviews. 2019 Jan 15;139(SI):71-82.
    2019-06-05 Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice European Journal of Pharmacology. 2019 Jun 5;852:265-273.
    2019-06 Identification of the PCA29 gene signature as a predictor in prostate cancer Journal of Bioinformatics and Computational Biology. 2019 Jun;17(3, SI):Article number 1940006.
    2019-05-29 Insights for the design of protein lysine methyltransferase G9a inhibitors Future Medicinal Chemistry. 2019 May 29;11(9):993-1014.
    2019-05-28 Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform Cancers. 2019 May 28;11(6):Article number 739.
    2019-05 Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents Future Medicinal Chemistry. 2019 May;11(9):959-974.
    2019-05 Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant Cell Chemical Biology. 2019 May;26(5):662-673.e7.
    2019-05 A novel mechanism of miRNA-mediated CBX8 associated with tumorigenesis in head and neck squamous cell carcinoma Journal of Clinical Oncology. 2019 May;37(15, Suppl. S):Abstract number e17534.
    2019-04-10 Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957.
    2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
    2019-04-01 The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone European Journal of Medicinal Chemistry. 2019 Apr 1;167:312-323.
    2019-03-28 Phase-changeable nanoemulsions for oral delivery of a therapeutic peptide: Toward targeting the pancreas for antidiabetic treatments using lymphatic transport Advanced Functional Materials. 2019 Mar 28;29(13): Article number 1809015.
    2019-03-15 Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation Communications Biology. 2019 Mar 15;2:Article number 105.
    2019-03-01 Interference of DNAJB6/MRJ isoform switch by morpholino inhibits replication of HIV-1 and RSV Molecular Therapy. Nucleic Acids. 2019 Mar 1;14:251-261.
    2019-03 Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors Bioorganic Chemistry. 2019 Mar;83:520-525.
    2019-03 Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A Journal of General Virology. 2019 Mar;100(3):457-470.
    2019-02-20 Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice Scientific Reports. 2019 Feb 20;9:Article number 2405.
    2019-01-03 KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC Oncogene. 2019 Jan 3;38(1):17-32.

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