國家衛生研究院 NHRI:
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    显示项目1-50 / 268. (共6页)
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    日期题名關聯
    2025-02-27 Orally bioavailable and site-selective covalent STING inhibitor derived from a macrocyclic marine diterpenoid Journal of Medicinal Chemistry. 2025 Feb 27;Article in Press.
    2025-02 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin[Erratum:Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.] Biochemical Pharmacology. 2025 Feb;232:Article number 116753.
    2025-01-05 Integrating ultrabright polymer dots and stereo NIR-II imager for assessing anti-angiogenic drugs in oral cancer model Journal of Cellular and Molecular Medicine. 2025 Jan 05;29(1):Article number e70324.
    2025-01 Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models Pharmacological Research. 2025 Jan;211:Article number 107556.
    2024-11-21 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia Cell Chemical Biology. 2024 Nov 21;31(11):1885-1898.e10.
    2024-11 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
    2024-06-01 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
    2024-05-30 Poly heterocyclic conjugates and their pharmaceutical uses ZA2022/12959/2024-05-30
    2024-03-26 Heterocyclic compounds and use thereof NZ730195/2024-03-26
    2024-02-16 Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo ACS Food Science and Technology. 2024 Feb 16;4(2):479-490.
    2024-01-23 Poly heterocyclic conjugates and their pharmaceutical uses US11878986/2024-01-23
    2024-01-14 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease SG11202101274X/2024-01-14
    2023-12-19 Heterocyclic compounds and use thereof CA2962329/2023-12-19
    2023-09-26 Composto de fórmula (i) e composição farmacêutica BR112017005713/2023-09-26
    2023-08-31 Dipicolylamine derivatives and their pharmaceutical uses IN448770/2023-08-31
    2023-08-15 Composto e composição farmacêutica BR112016027078-9/2023-08-15
    2023-07-20 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
    2023-06-01 增加細胞吞噬作用之方法 TWI804339/2023-06-01
    2023-04-21 多雜環小分子藥物偶合物及其用途 TWI799896/2023-04-21
    2023-03-08 헤테로사이클릭 화합물과 이의 용도 KR10-2509431/2023-03-08
    2023-03-03 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease IN424040/2023-03-03
    2023-02-10 Heterocyclic compounds and use thereof IN421151/2023-02-10
    2023-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
    2023-01-27 苯並咪唑化合物及其在製備治療阿茲海默症或亨丁頓氏症的藥物中的用途 HK40053325/2023-01-27
    2023-01-26 苯并咪唑化合物及其在製備治療阿茲海默症或亨丁頓氏症的藥物中的用途 J/006659/2023-01-26
    2023-01-24 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease CA3109623/2023-01-24
    2023-01-19 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.] Pharmaceutics. 2023 Jan 19;15(2):Article number 342.
    2023-01-10 Dipicolylamine derivatives and their pharmaceutical uses CA2949663/2023-01-10
    2022-12-05 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
    2022-12-02 Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies Journal of Medical Virology. 2022 Dec 2;95:Article number e28370.
    2022-11-15 BPR0C261, an analogous of microtubule disrupting agent D-24851 enhances the radiosensitivity of human non-small cell lung cancer cells via p53-dependent and p53-independent pathways International Journal of Molecular Sciences. 2022 Nov 15;23(22):Article number 14083.
    2022-11-01 Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis Clinica Chimica Acta. 2022 Nov 1;536:45-55.
    2022-11 Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
    2022-10-21 抗人神經降壓素受體抗體及其用途 TWI781647/2022-10-21
    2022-10-13 Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate Journal of Medicinal Chemistry. 2022 Oct 13;65(19):12802-12824.
    2022-10-03 Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730.
    2022-08-23 苯并咪唑化合物及其在制备治疗阿兹海默症或亨丁顿氏症的药物中的用途 CN113613652/2022-08-23
    2022-07-21 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.
    2022-07-20 Dipicolylamine derivatives and their pharmaceutical uses EP3145922/2022-07-20
    2022-07-11 嘧啶化合物及其醫藥用途 TWI770858/2022-07-11
    2022-06-21 Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids Pharmaceutics. 2022 Jun 21;14(7):Article number 1316.
    2022-05-31 벤즈이미다졸 화합물 및 알츠하이머 질환 또는 헌팅톤병을 치료하기 위한 그의 용도 KR 10-2405760/2022-05-31
    2022-05-02 Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection Frontiers in Immunology. 2022 May 2;13:Article number 872047.
    2022-04-13 디피콜릴아민 유도체 및 이들의 약제학적 용도 KR10-2387835/2022-04-13
    2022-03-14 ベンズイミダゾール化合物,及びアルツハイマー病又はハンチントン病の治療のためのその使用 JP7035275/2022-03-14
    2022-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
    2022-02-15 Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates Frontiers in Chemistry. 2022 Feb 15;9:Article number 822587.
    2022-01-07 雜環化合物及其用途 HK1238644/2022-01-07
    2022-01-05 雜環化合物及其用途 J/005468/2022-01-05
    2021-12 Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice Biomedical Journal. 2021 Dec;44(6 Suppl 2):S210-S217.

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