國家衛生研究院 NHRI:
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    日期題名關聯
    2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
    2011-03-07 2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors ChemMedChem. 2011 Mar 7;6(3):450-456.
    2011-03 Potent EGFR tyrosine kinase inhibitors as anticancer agents Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI.
    2011-03 SAR studies of quinoline derivatives as novel anti-influenza agents Abstracts of Papers - American Chemical Society. 2011 Mar;241:81-MEDI.
    2010-12-01 吲哚化合物 ZL200480034988.8/2010-12-01
    2010-12-01 抗肿瘤化合物 ZL200580045509.7/2010-12-01
    2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
    2010-10-06 吡咯烷化合物 ZL200580009891.6/2010-10-06
    2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists ChemMedChem. 2010 Oct;5(10):1707-1716.
    2010-09 Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes PLoS ONE. 2010 Sep;5(9):Article number e12564.
    2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332.
    2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 Anticancer Research. 2010 Jul;30(7):2813-2822.
    2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification Journal of Medicinal Chemistry. 2010 Jun 15;53(13):4980-4988.
    2010-06 Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis Journal of Medicinal Chemistry. 2010 Jun;53(11):4545-4549.
    2010-03-30 Pyrrolidine compounds US7687504B2/2010-03-30
    2010-03-11 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313.
    2010-02-25 Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives Journal of Medicinal Chemistry. 2010 Feb 25;53(4):1519-1533.
    2010-02-23 Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity Journal of Biomedical Science. 2010 Feb 23;17:Article number 13.
    2010-02-01 Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor ChemMedChem. 2010 Feb 1;5(2):255-267.
    2010-02 Comparative molecular field analysis of anti-tubulin agents with indole ring binding at the colchicine binding site Journal of Theoretical and Computational Chemistry. 2010 Feb;9(1):279-291.
    2010-01 BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses Journal of Antimicrobial Chemotherapy. 2010 Jan;65(1):63-71.
    2009-12-15 Indole compounds US7632955B2/2009-12-15
    2009-12-01 芳香羰吲哚化合物 I317634/2009-12-01
    2009-09 Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development EJC Supplements. 2009 Sep;7(2):96.
    2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.

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