國家衛生研究院 NHRI:
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12189/12972 (94%)
造訪人次 : 966278      線上人數 : 863
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    主頁登入上傳說明關於NHRI管理 到手機版
    會議論文/會議摘要 [30/48]
    專利 [0/42]

    類別統計

    近3年內發表的文件:13(9.15%)
    含全文筆數:142(100.00%)

    文件下載次數統計
    下載大於0次:142(100.00%)
    下載大於100次:138(97.18%)
    檔案下載總次數:84136(82.42%)

    最後更新時間: 2024-12-04 02:43


    上傳排行

    資料載入中.....

    下載排行

    資料載入中.....

    RSS Feed RSS Feed
    跳至:
    或輸入年份:
    由新到舊排序 由最舊的開始

    顯示項目101-125 / 142. (共6頁)
    << < 1 2 3 4 5 6 > >>
    每頁顯示[10|25|50]項目

    日期題名關聯
    2008-05 Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana Phytotherapy Research. 2008 May;22(5):605-613.
    2008-04-15 Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus Biochemical Pharmacology. 2008 Apr;75(8):1601-1609.
    2008-03-13 Synthesis and biological evaluation of 1-methyl-2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors Journal of Medicinal Chemistry. 2008 Mar;51(5):1464-1468.
    2008-03-10 Reactions of 2-hydroxybenzophenones with Corey-Chaykovsky reagent Tetrahedron. 2008 Mar;64(11):2586-2595.
    2008-03-01 Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold Bioorganic and Medicinal Chemistry Letters. 2008 Mar;18(5):1623-1627.
    2008-02-07 First total syntheses of (+/-)-annuionone B and (+/-)-tanarifuranonol Organic Letters. 2008 Feb 7;10(3):449-452.
    2008-02 A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells Anti-Cancer Drugs. 2008 Feb;19(2):151-158.
    2007-12 Strategies of development of antiviral agents directed against influenza virus replication Current Pharmaceutical Design. 2007 Dec;13(34):3531-3542.
    2007-09-06 4-and 5-aroylindoles as novel classes of potent antitubulin agents Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552.
    2007-07-31 Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil British Journal of Cancer. 2007 Jul;97(3):334-344.
    2007-07 Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes Drug Metabolism and Disposition. 2007 Jul;35(7):1042-1049.
    2007-03-01 3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes Bioorganic and Medicinal Chemistry Letters. 2007 Mar;17(5):1274-1279.
    2007-02-08 Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells Cancer Letters. 2007 Feb;246(1-2):237-252.
    2007-02-01 Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study Journal of Chromatography B. 2007 Feb;846(1-2):162-168.
    2006-12 Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats Journal of Food and Drug Analysis. 2006 Dec;14(4):329-333.
    2006-11-16 7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659.
    2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424.
    2006-10 Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents ChemMedChem. 2006 Oct;1(10):1106-1118.
    2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease Journal of Medicinal Chemistry. 2006 Aug;49(17):5154-5161.
    2006-07 Antiviral drug discovery against SARS-CoV Current Medicinal Chemistry. 2006 Jul;13(17):2003-2020.
    2006-06-15 Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors Bioorganic and Medicinal Chemistry Letters. 2006 Jun;16(12):3268-3272.
    2006-06-15 Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies Journal of Medicinal Chemistry. 2006 Jun;49(12):3485-3495.
    2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712.
    2006-05 Antitubulin agents for the treatment of cancer - a medicinal chemistry update Expert Opinion on Therapeutic Patents. 2006 May;16(5):647-691.
    2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216.

    顯示項目101-125 / 142. (共6頁)
    << < 1 2 3 4 5 6 > >>
    每頁顯示[10|25|50]項目

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋