| 2015-07-31 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物 |
HK1151694/2015-07-31 |
|
| 2015-07-29 |
脯氨酸衍生物 |
ZL201080002506.6/2015-07-29 |
|
| 2015-07-22 |
作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 |
ZL200980144458.1/2015-07-22 |
|
| 2015-07 |
Development and application of a fluorescent glucose uptake assay for the high-throughput screening of non-glycoside SGLT2 inhibitors |
European Journal of Pharmaceutical Sciences. 2015 Jul;74:40-44. |
 |
| 2015-07 |
Pharmacological induction of human fetal globin gene in hydroxyurea-resistant primary adult erythroid cells |
Molecular and Cellular Biology. 2015 Jul;35(14):2541-2553. |
|
| 2015-07 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations |
European Journal of Medicinal Chemistry. 2015 Jul;100:151-161. |
|
| 2015-07 |
Biological evaluation of secondary metabolites from the root of machilus obovatifolia |
Chemistry and Biodiversity. 2015 Jul;12(7):1057-1067. |
|
| 2015-06-29 |
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification |
Scientific Reports. 2015 Jun 29;5:Article number 11702. |
|
| 2015-06-16 |
Anchor-based classification and type-C inhibitors for tyrosine kinases |
Scientific Reports. 2015 Jun 16;5:Article number 10938. |
|
| 2015-06-15 |
Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents |
European Journal of Medicinal Chemistry. 2015 Jun 15;98:1-12. |
|
| 2015-06-15 |
The total synthesis of retrojusticidin B, justicidin E, and helioxanthin |
Journal of Organic Chemistry. 2015 Jun 15;80(13):6708-6714. |
|
| 2015-06-01 |
治療C型肝炎病毒感染之醫藥組成物 |
I486160/2015-06-01 |
|
| 2015-05-29 |
Proline derivatives |
JP5753185/2015-05-29 |
|
| 2015-05 |
Assessment of dermal absorption of DEET-containing insect repellent and oxybenzone-containing sunscreen using human urinary metabolites |
Environmental Science and Pollution Research. 2015 May;22(9):7062-7070. |
|
| 2015-05 |
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis |
Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504. |
|
| 2015-05 |
Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
Biochemical Pharmacology. 2015 May;95(1):28-37. |
|
| 2015-05 |
Enhanced antitumor activity of rapamycin and genipin, a UCP-2 inhibitor, in lung cancer |
Journal of Clinical Oncology. 2015 May;33(15, Suppl.):e13595. |
|
| 2015-04-14 |
Fused multicyclic compounds as protein kinase inhibitors |
US9006252B2/2015-04-14 |
|
| 2015-04 |
IL-1beta promotes malignant transformation and tumor aggressiveness in oral cancer |
Journal of Cellular Physiology. 2015 APR;230(4):875-884. |
|
| 2015-04 |
Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-Terminal half of Dengue Virus NS2A involved in viral RNA replication and virus assembly and secretion |
Journal of Virology. 2015 Apr;89(8):4281-4295. |
|
| 2015-04 |
Tylophorine compounds exert anti-cancer activity by targeting a ribonucleoprotein complex containing caprin-1 and c-Myc mRNA |
FASEB Journal. 2015 Apr;29(1, Suppl.):Abstract number LB132 |
|
| 2015-03 |
Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury |
Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325. |
|
| 2015-02-24 |
Pyrazole compounds |
US8962845/2015-02-24 |
|
| 2015-02-11 |
吡唑類化合物 |
I472514/2015-02-11 |
|
| 2015-02 |
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors |
Journal of Medicinal Chemistry. 2015 Feb;58(3):1452-1465. |
|
| 2015-02 |
Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget |
Oncotarget. 2015 Feb;6(4):2148-2163. |
|
| 2015-01-02 |
KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity |
Journal of Biomedical Science. 2015 Jan 2;22:Article number 2. |
|
| 2015-01 |
1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells |
European Journal of Medicinal Chemistry. 2015 Jan;89:320-330. |
|
| 2015-01 |
Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity |
Journal of Computer-Aided Molecular Design. 2015 Jan;29(1):89-100. |
|
| 2015-01 |
Two new labdane-type diterpene acids from the wood of cunninghamia konishii |
Helvetica Chimica Acta. 2015 Jan;98(1):123-127. |
|
| 2014-12-01 |
Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling |
Nucleic Acids Research. 2014 Dec 1;42(21):13012-13025. |
|
| 2014-12 |
Large isoform of mammalian relative of dnaJ is a major determinant of human susceptibility to HIV-1 infection |
EBioMedicine. 2014 Dec;1(2-3):126-132. |
|
| 2014-12 |
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71 |
Antiviral Research. 2014 Dec;112:18-25. |
|
| 2014-11-20 |
The combination effects of LiCl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replication |
PLoS ONE. 2014 Nov 20;9(11):Article number e111331. |
|
| 2014-11-19 |
咪唑-4-酮及咪唑-4-硫酮化合物 |
ZL200910006503.9/2014-11-19 |
|
| 2014-11 |
Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction |
Cellular Microbiology. 2014 Nov;16(11):1603-1618. |
|
| 2014-11 |
Chemical constituents and cytotoxic activities from the fruits of Reevesia formosana |
Planta Medica. 2014 Nov;80(16):1541. |
|
| 2014-11 |
Chemical constituents and cytotoxic activities from the root and the stem of Reevesia formosana |
Planta Medica. 2014 Nov;80(16):1541. |
|
| 2014-11 |
Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent |
European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93. |
|
| 2014-11 |
Cytokine induces MIR-424 expression and modulates SOCS2/STAT5 signaling pathway in oral cancer |
European Journal of Cancer. 2014 Nov;50(Suppl. 6):147. |
|
| 2014-11 |
CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors |
European Journal of Cancer. 2014 Nov;50(Suppl. 6):19-20. |
|
| 2014-10-29 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物 |
ZL200980115577.4/2014-10-29 |
|
| 2014-10-21 |
化合物於製造治療病毒感染的藥物之用途 |
I457121/2014-10-21 |
|
| 2014-10 |
Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer |
Expert Opinion on Investigational Drugs. 2014 Oct;23(10):1333-1348. |
|
| 2014-10 |
Use of highly variable gene (yycH) as DNA marker to resolve interspecific relationships within the Lactobacillus casei group and a target for developing novel species-specific PCR primers |
European Food Research and Technology. 2014 Oct;239(4):719-724. |
|
| 2014-10 |
Manganese(III)-catalyzed oxidative cyclization of aryl 1-cyanoalk-5-ynyl ketone systems: A convenient and general approach to cyclopenta[b]naphthalene derivatives |
Advanced Synthesis and Catalysis. 2014 Oct;356(14-15):3025-3038. |
|
| 2014-10 |
YYEI motif is critical to oncogenicity of 14-3-3 proteins |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 3527. |
|
| 2014-10 |
Optimization of 5,6-fused pyrimidine-based kinase inhibitors by computer-aided drug design for the treatment of AML |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 2530. |
|
| 2014-10 |
Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756. |
|
| 2014-10 |
Copper-chelator exerts synergistic interaction with platinum drugs through modulating copper transporters in oxaliplatin-resistant human gastric cancer cell |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 3753. |
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