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Showing items 101-150 of 231. (5 Page(s) Totally) << < 1 2 3 4 5 > >> View [10|25|50] records per page

Date	Title	Relation
2013-01	Substituent effects on the photorearrangements of unsymmetrically substituted diazinobarrelenes	RSC Advances. 2013 Jan;3(4):1165-1178.
2012-12	An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold	Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554.
2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	ChemMedChem. 2012 Sep;7(9):1546-1550.
2012-08-24	Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts	PLoS ONE. 2012 Aug 24;7(8):Article number e43314.
2012-05-11	作為極光激酶抑制劑之稠合雙環嘧啶化合物	I363627/2012-05-11
2012-04-21	吡咯啉啶化合物	I362388/2012-04-21
2012-03-25	Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors	Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
2012-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	US8138194B2/2012-03-20
2012-03-06	Indole compounds	CA2437104/2012-03-06
2012-02	Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus	Antimicrobial Agents and Chemotherapy. 2012 Feb;56(2):647-657.
2012-01-17	Pyrrolidine compounds	CA2559611/2012-01-17
2012-01	A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors	Anticancer Research. 2012 Jan;32(1):147-151.
2011-11-15	Coumarin compounds and their use for treating cancer	US8058427B2/2011-11-15
2011-09-23	BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo	European Journal of Cancer. 2011 Sep 23;47:S127.
2011-09	Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents	European Journal of Medicinal Chemistry. 2011 Sep;46(9):3623-3629.
2011-09	Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway	Journal of Virology. 2011 Sep;85(17):9114-9126
2011-08	BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells	PLoS ONE. 2011 Aug;6(8):Article number e23485.
2011-07-11	抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物	I344959/2011-07-11
2011-06-21	抑制冠狀病毒之醫藥組合物	I343809/2011-06-21
2011-06-21	抑制冠狀病毒之醫藥組合物	I343808/2011-06-21
2011-06-21	抑制冠狀病毒之醫藥組合物	I343810/2011-06-21
2011-06	Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10)	Expert Opinion on Therapeutic Patents. 2011 Jun;21(6):857-884.
2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
2011-04-06	Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders	EP1506960/2011-04-06
2011-04	Antivascular activities of novel tubulin binding agent BPR0L075	Cancer Research. 2011 Apr;71:Abstract number 5309.
2011-03-27	Design and synthesis of potent Aurora kinase inhibitors	Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
2011-03-07	2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors	ChemMedChem. 2011 Mar 7;6(3):450-456.
2011-03	Potent EGFR tyrosine kinase inhibitors as anticancer agents	Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI.
2011-03	SAR studies of quinoline derivatives as novel anti-influenza agents	Abstracts of Papers - American Chemical Society. 2011 Mar;241:81-MEDI.
2010-12-01	吲哚化合物	ZL200480034988.8/2010-12-01
2010-12-01	抗肿瘤化合物	ZL200580045509.7/2010-12-01
2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
2010-10-06	吡咯烷化合物	ZL200580009891.6/2010-10-06
2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	ChemMedChem. 2010 Oct;5(10):1707-1716.
2010-09	Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes	PLoS ONE. 2010 Sep;5(9):Article number e12564.
2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332.
2010-07	Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075	Anticancer Research. 2010 Jul;30(7):2813-2822.
2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Journal of Medicinal Chemistry. 2010 Jun 15;53(13):4980-4988.
2010-06	Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis	Journal of Medicinal Chemistry. 2010 Jun;53(11):4545-4549.
2010-03-30	Pyrrolidine compounds	US7687504B2/2010-03-30
2010-03-11	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313.
2010-02-25	Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives	Journal of Medicinal Chemistry. 2010 Feb 25;53(4):1519-1533.
2010-02-23	Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity	Journal of Biomedical Science. 2010 Feb 23;17:Article number 13.
2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	ChemMedChem. 2010 Feb 1;5(2):255-267.
2010-02	Comparative molecular field analysis of anti-tubulin agents with indole ring binding at the colchicine binding site	Journal of Theoretical and Computational Chemistry. 2010 Feb;9(1):279-291.
2010-01	BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses	Journal of Antimicrobial Chemotherapy. 2010 Jan;65(1):63-71.
2009-12-15	Indole compounds	US7632955B2/2009-12-15
2009-12-01	芳香羰吲哚化合物	I317634/2009-12-01
2009-09	Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development	EJC Supplements. 2009 Sep;7(2):96.
2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.

Showing items 101-150 of 231. (5 Page(s) Totally) << < 1 2 3 4 5 > >> View [10|25|50] records per page