國家衛生研究院 NHRI:
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    日期題名關聯
    2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor ChemMedChem. 2013 Jan;8(1):136-148.
    2013-01 Substituent effects on the photorearrangements of unsymmetrically substituted diazinobarrelenes RSC Advances. 2013 Jan;3(4):1165-1178.
    2012-12 An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554.
    2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization ChemMedChem. 2012 Sep;7(9):1546-1550.
    2012-08-24 Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts PLoS ONE. 2012 Aug 24;7(8):Article number e43314.
    2012-05-11 作為極光激酶抑制劑之稠合雙環嘧啶化合物 I363627/2012-05-11
    2012-04-21 吡咯啉啶化合物 I362388/2012-04-21
    2012-03-25 Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
    2012-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors US8138194B2/2012-03-20
    2012-03-06 Indole compounds CA2437104/2012-03-06
    2012-02 Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus Antimicrobial Agents and Chemotherapy. 2012 Feb;56(2):647-657.
    2012-01-17 Pyrrolidine compounds CA2559611/2012-01-17
    2012-01 A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors Anticancer Research. 2012 Jan;32(1):147-151.
    2011-11-15 Coumarin compounds and their use for treating cancer US8058427B2/2011-11-15
    2011-09-23 BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo European Journal of Cancer. 2011 Sep 23;47:S127.
    2011-09 Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents European Journal of Medicinal Chemistry. 2011 Sep;46(9):3623-3629.
    2011-09 Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway Journal of Virology. 2011 Sep;85(17):9114-9126
    2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells PLoS ONE. 2011 Aug;6(8):Article number e23485.
    2011-07-11 抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物 I344959/2011-07-11
    2011-06-21 抑制冠狀病毒之醫藥組合物 I343809/2011-06-21
    2011-06-21 抑制冠狀病毒之醫藥組合物 I343808/2011-06-21
    2011-06-21 抑制冠狀病毒之醫藥組合物 I343810/2011-06-21
    2011-06 Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10) Expert Opinion on Therapeutic Patents. 2011 Jun;21(6):857-884.
    2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
    2011-04-06 Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders EP1506960/2011-04-06

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