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日期	题名	關聯
2025-01	Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design	Bioorganic Chemistry. 2025 Jan;154:Article number 108019.
2025-01	Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	Pharmacological Research. 2025 Jan;211:Article number 107556.
2024-12-30	Novel naphthyridones targeting pannexin 1 for colitis management	Advanced Science. 2024 Dec 30;Article in Press.
2024-12	Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma	International Journal of Biological Macromolecules. 2024 Dec;283(Part 1):Article number 137296.
2024-11-07	Discovery of DYRK1A inhibitors as potential treatment of pancreatic ductal adenocarcinoma (PDAC)	Asia-Pacific Journal of Clinical Oncology. 2024 Nov 07;20:116.
2024-11-07	Novel approach to anti-tumour and anti-SARS-COV-2 drugs by modulating sialylation of N-glycans	Asia-Pacific Journal of Clinical Oncology. 2024 Nov 07;20:116-117.
2024-11	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
2024-11	Epithelial cell adhesion molecule induces induces Wnt receptor transcription to promote colorectal cancer progression	Asia-Pacific Journal of Clinical Oncology. 2024 Nov;20:121.
2024-06-24	Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease	European Polymer Journal. 2024 Jun 24;214:Article number 113151.
2024-06-24	Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment	Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press.
2024-05-09	Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function	Journal of Biomedical Science. 2024 May 09;31:Article number 46.
2023-11-03	Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone	Organic Letters. 2023 Nov 3;25(43):7757-7762.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2023-10	Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs	Annals of Oncology. 2023 Oct;34(Suppl. 2):S214.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-09-12	A critical overview of current progress for COVID-19: Development of vaccines, antiviral drugs, and therapeutic antibodies	Journal of Biomedical Science. 2022 Sep 12;29:Article number 68.
2022-08-09	Recent advances in total synthesis of natural products by masked ortho-benzoquinones	Journal of the Chinese Chemical Society. 2022 Aug 09;69(8):1210-1222.
2022-05-09	Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer	Journal of Biomedical Science. 2022 May 9;29:Article number 29.
2022-04-06	Identification of entry inhibitors against delta and omicron variants of SARS-CoV-2	International Journal of Molecular Sciences. 2022 Apr 6;23(7):Article number 4050.
2022-01-21	Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma	Journal of Biomedical Science. 2022 Jan 21;29:Article number 5.
2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-07-16	Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens	Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
2021-04-16	Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors	Organic Process Research and Development. 2021 Apr 16;25(4):817-830.
2021-04-13	Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kükenthal, 1908)	Tetrahedron Letters. 2021 Apr 13;69:Article number 152976.

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