| 2025-04 |
Junceellolide Q, a new polyacetoxybriarane from the delicate sea whip octocoral Junceella fragilis |
Phytochemistry Letters. 2025 Apr;66:9-14. |
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| 2025-03-25 |
KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules |
Developmental Cell. 2025 Mar 25;Article in Press. |
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| 2025-03-24 |
Identification and biological evaluation of a novel CLK4 inhibitor targeting alternative splicing in pancreatic cancer using structure-based virtual screening |
Advanced Science. 2025 Mar 24;Article in Press. |
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| 2025-03-21 |
Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity |
EMBO Molecular Medicine. 2025 Mar 21;Article in Press. |
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| 2025-03-11 |
Tumor cell-derived ISG15 promotes fibroblast recruitment in oral squamous cell carcinoma via CD11a-dependent glycolytic reprogramming |
Oncogenesis. 2025 Mar 11;14:Article number 6. |
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| 2025-03-10 |
CXCR4 antagonist-loaded nanoparticles reprogram the tumor microenvironment and enhance immunotherapy in hepatocellular carcinoma |
Journal of Controlled Release. 2025 Mar 10;379:967-981. |
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| 2025-03-05 |
Upregulation of cathepsin S expression contributes to neuronal damage following kainic acid-induced status epilepticus |
Journal of Neurochemistry. 2025 Mar 05;169(3):Article number e70037. |
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| 2025-03-05 |
Nitrogen, oxygen, and sulphur heterocycles as potent anti-inflammatory agents: Insight into the synthetic routes |
Chemistryselect. 2025 Mar 05;10(9):Article number e202403824. |
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| 2025-02-27 |
Orally bioavailable and site-selective covalent STING inhibitor derived from a macrocyclic marine diterpenoid |
Journal of Medicinal Chemistry. 2025 Feb 27;Article in Press. |
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| 2025-02-03 |
Synthesis, anticancer evaluation and structure-activity relationship of Taiwanin a derivatives |
Chemistry of Natural Compounds. 2025 Feb 03;61:11-18. |
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| 2025-02 |
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin[Erratum:Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.] |
Biochemical Pharmacology. 2025 Feb;232:Article number 116753. |
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| 2025-02 |
Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection |
Biomedicine and Pharmacotherapy. 2025 Feb;183:Article number 117851. |
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| 2025-01-05 |
Integrating ultrabright polymer dots and stereo NIR-II imager for assessing anti-angiogenic drugs in oral cancer model |
Journal of Cellular and Molecular Medicine. 2025 Jan 05;29(1):Article number e70324. |
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| 2025-01-03 |
Prevotella intermedia protease interpain A promotes human cancer cell lines proliferation and migration |
Cancer Science. 2025 Jan 03;116(S1):643. |
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| 2025-01 |
Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design |
Bioorganic Chemistry. 2025 Jan;154:Article number 108019. |
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| 2025-01 |
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models |
Pharmacological Research. 2025 Jan;211:Article number 107556. |
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| 2024-12-30 |
Novel naphthyridones targeting pannexin 1 for colitis management |
Advanced Science. 2024 Dec 30;Article in Press. |
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| 2024-12-23 |
An integrated testing strategy and online tool for assessing skin sensitization of agrochemical formulations |
Toxics. 2024 Dec 23;12(12):Article number 936. |
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| 2024-12 |
Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma |
International Journal of Biological Macromolecules. 2024 Dec;283(Part 1):Article number 137296. |
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| 2024-12 |
Alkoxylation of ketone mediated by N-heterocyclic carbene borane and sulfuric acid in alcohol |
Asian Journal of Organic Chemistry. 2024 Dec;13(12):Article number e202400436. |
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| 2024-11-30 |
Generation of quaternary carbons in cycloalkanones and lactones with arynes through a domino process |
Journal of Organic Chemistry. 2024 Nov 30;89(24):18393-18399. |
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| 2024-11-26 |
Development of potent and selective inhibitors of methylenetetrahydrofolate dehydrogenase 2 for targeting acute myeloid leukemia: Sar, structural insights, and biological characterization |
Journal of Medicinal Chemistry. 2024 Nov 26;67(23):21106-21125. |
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| 2024-11-21 |
Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia |
Cell Chemical Biology. 2024 Nov 21;31(11):1885-1898.e10. |
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| 2024-11-13 |
Beta-d-Ribofuranose as a core with a phosphodiester moiety as the enzyme recognition site for codrug development |
Organic letters. 2024 Nov 13;Article in Press. |
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| 2024-11-07 |
Discovery of DYRK1A inhibitors as potential treatment of pancreatic ductal adenocarcinoma (PDAC) |
Asia-Pacific Journal of Clinical Oncology. 2024 Nov 07;20:116. |
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| 2024-11-07 |
Novel approach to anti-tumour and anti-SARS-COV-2 drugs by modulating sialylation of N-glycans |
Asia-Pacific Journal of Clinical Oncology. 2024 Nov 07;20:116-117. |
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| 2024-11 |
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration |
Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790. |
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| 2024-11 |
Epithelial cell adhesion molecule induces induces Wnt receptor transcription to promote colorectal cancer progression |
Asia-Pacific Journal of Clinical Oncology. 2024 Nov;20:121. |
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| 2024-09 |
Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy |
APL Bioengineering. 2024 Sep;8:Article number 036107. |
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| 2024-08-14 |
Induction of thymus atrophy and disruption of thymocyte development by fipronil through dysregulation of IL-7-associated genes |
Chemical Research in Toxicology. 2024 Aug 14;Article in Press. |
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| 2024-08-02 |
A novel multitask learning algorithm for tasks with distinct chemical space: zebrafish toxicity prediction as an example |
Journal of Cheminformatics. 2024 Aug 02;16:Article number 91. |
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| 2024-07-31 |
Incorporating tissue-specific gene expression data to improve chemical-disease inference of in silico toxicogenomics methods |
Journal of Xenobiotics. 2024 Jul 31;14(3):1023-1035. |
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| 2024-07-17 |
雜環化合物及其用途 |
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| 2024-07-04 |
Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells |
Cells. 2024 Jul 04;13(13):Article number 1146. |
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| 2024-06-24 |
Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease |
European Polymer Journal. 2024 Jun 24;214:Article number 113151. |
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| 2024-06-24 |
Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment |
Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press. |
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| 2024-06-18 |
Method of the preparation of fused multicyclic compounds |
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| 2024-06-11 |
稠合多環化合物之合成方法 |
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| 2024-06-01 |
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus |
Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779. |
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| 2024-05-30 |
Poly heterocyclic conjugates and their pharmaceutical uses |
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| 2024-05-28 |
Chlorine-containing polyacetoxybriarane diterpenoids from the octocoral Junceella fragilis |
RSC Advances. 2024 May 28;14:17195-17201. |
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| 2024-05-09 |
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function |
Journal of Biomedical Science. 2024 May 09;31:Article number 46. |
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| 2024-05-01 |
Thiazolidinone compounds and use thereof |
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| 2024-04-26 |
The method of the preparation of fused multicyclic compounds |
AU2022201063/2024-04-26 |
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| 2024-04-16 |
Inhibitors of positive strand RNA viruses |
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| 2024-04-03 |
抗-乙型澱粉樣蛋白抗體及其用途 |
J/007827/2024-04-03 |
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| 2024-04 |
Design, synthesis, and anticancer evaluation of 1-benzo[1,3]dioxol-5-yl-3-N-fused heteroaryl indoles |
Molecular Diversity. 2024 Apr;28(2):595-608. |
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| 2024-04 |
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir |
Antimicrobial Agents and Chemotherapy. 2024 Apr 3;68(4):Article number e0095623 |
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| 2024-04 |
Reducing brain Abeta burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice |
Biomedicine and Pharmacotherapy. 2024 Apr;173:Article number 116404. |
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| 2024-03-26 |
Heterocyclic compounds and use thereof |
NZ730195/2024-03-26 |
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